The diminishing effect with regular use of the same dose of a drug is called?

The diminishing effect with regular use of the same dose of a drug is called?

• A. Tolerance
• B. Consolidation Theory
• C. Activation Synthesis
• D. Circadian Rhythm

Answer: (A)

Tolerance is the diminishing effect that occurs with regular use of the same dose of a drug. The body adapts over time—receptors may become less responsive, or metabolic enzymes may increase—so the same amount of drug produces a weaker effect. As a result, a higher dose may be needed to achieve the same level of effect. This differs from sleep-related theories like Consolidation Theory or Activation-Synthesis and from circadian rhythm, which describe other aspects of sleep biology. For example, regular alcohol use can lead to needing more alcohol to achieve the same level of intoxication due to tolerance.

Tolerance is the diminishing effect that occurs with regular use of the same dose of a drug. The body adapts over time—receptors may become less responsive, or metabolic enzymes may increase—so the same amount of drug produces a weaker effect. As a result, a higher dose may be needed to achieve the same level of effect. This differs from sleep-related theories like Consolidation Theory or Activation-Synthesis and from circadian rhythm, which describe other aspects of sleep biology. For example, regular alcohol use can lead to needing more alcohol to achieve the same level of intoxication due to tolerance.